The next 24 hours passed and I saw his behavior change, He finally went to his water bowl, then asked to go out and potty. If you are looking for a quick and easy way to help your dogs allergies, I suggest you try my supplement, Dr Jones Ultimate Canine Health Formula. Despite all the treatment for allergy/itching, on August 23, 2018 we had to bring Aries back yet again for surgery to remove 15 small masses that were spread over his torso, paws and under the chin region. When we returned home he had trouble climbing the stairs.The next morning he couldnt walk. Lastly, I think you choose to bash a drug just to sell your supplement. At this point our cost has been $2200. Here is my dilemma. See more at: http://news.zoetis.com/press-release/investors/zoetis-reports-fourth-quarter-and-full-year-2014-results#sthash.hYHWSMPk.dpuf, Revenue of nearly 5 billion dollarsa pretty heft marketing budget, along with an endless array of paid consultants/lobbyists to ensure that governing bodies dont over regulate and allow the company to keep on selling drugs, regardless of the occasional dead dog. She said if he was human, they would say he was anorexic. A blinded, randomized, placebo-controlled trial of the efficacy and safety of the Janus kinase inhibitor oclacitinib (Apoquel) in client-owned dogs with atopic dermatitis. But, I did notice your office carried CET chews, Metacam, and Baytril. Can you tell me a little more about the dog's situation? Drugs that suppress the immune system Its going to be hard to give up a prescription that has made such a difference for our girl, but I also know that our vet has her best interest in mind. She was refusing to eat out of her bowl which was a red flag because our cocker spaniel is OBSESSEd with food ( I think she likes food more than she likes us ?). Hes on IV fluids but not expected to live more than a week. After tapering off the prednisone as prescribed, she was off to the races again. He ended up in shock and went into V Tach and the cardiologist put him on a procainamide drip to stop the VT and stabilize him, which worked, but who knows for how long. I noticed that he seemed a little lethargic after the first pill, but didnt feel alarmed since its supposed to do that. If you've a medium or small-sized pup the . I know that an itching dog suffers, but I will try whatever I can to give her to be comfortable, and I know between the prednisone and apoquel she is probably being killed from the inside and I cannot do that to her. I can not believe this is on the market with how many dogs have had issues from it. I am looking for suggestions on what to do. Dogs have 10 times more mast cells on their skin than people do. P.S. The above mentioned worked but she also added Atopica for 3 5 months to sustain the gut so he wouldnt itch anymore. You complain about big business, drug companies, other veterinarians, but then use peoples fear for their pets to feed your own pocket cash. Nothing major, but different. which is causing more messes to clean up. document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); Veterinarian, author, advocate for alternative, natural solutions for dog and cat health, Dr. Andrew Jones, DVM My 11 year old shih tzu has really terrible allergies once we moved from a large city to the suburbs he went downhill with allergies, it literally only took 4 hours before he started oozing green from his eyes. 8 3/4 yr old unknown mix (black & tan head, white with black spotted body & pink skin) to the vet after almost 8 years. The active ingredient in this medication is called oclacitinib. I am taking him to the Vet and will ask if this is Black Skin Disease, or Cushings. She is on Natural Balance fish and sweet potato formula and same brand of treats as she is allergic to wheat, gluten, chicken and beef. My dog has the latter. Yes your pet sure can. Moderate Interactions. Reading the experiences above, I now figure that his stomach is upset. My Yorkie/jack Russell, around 8 years old is supposedly allergic to fleas, around 20lbs. Decided to take him to ER. FDA approval of APOQUEL is based on results of two clinical trials conducted in the Its been 2yrs of no Atopica. Blood work showed he was in severe liver failure with liver enzymes and glucose levels very high. I saw another yorkies mom on here post the almost identical thing as my girl is. Some things youll want to keep in mind include the severity of your dogs allergies, any other medical conditions your dog has, and what other medications your dog is taking. Carprofen was previously used in human medicine for over 10 years (1985-1995). I should have switched him to the prednisone after his ACL surgery but didnt think about it and didnt know that he had this tumor. So after $1,100. Apoquel wont work for my pin , her itching decreased, but never stopped, and it has side effects. She died in my arms on the way to the vet.My Zoey is gone and I am heart broken. I went to a different vet than prescribed the Apoquel and he reported having seen this in other dogs in response to Apoquel. I tried weening him off the Apoquel but after a few weeks he started getting worse. I will also take my other boy off this medication. esophagus to close keeping it enlarged (side effect). Zyrtec, Claritin, and Benadryl are just some of the meds that both humans and dogs can take safely. I cant say enough how appreciative I am this drug came along! Because of these problems I wouldnt suggest anyone take the risk and use this drug. Thanks for sharing and I hope your dog fully recovers! The other option would have probably would have been a lot worse. All of the sudden it clicked. It was told to us in private that the long term effects of the Apoquel could be the cause of her cancer. Euthanasia 12-5-2017. You can contact Zoetis Inc at 1-888-963-8471. I withheld the medication to see if he got worse, and called the vet. By example, many that are on chemo come to us for high dose IV vitamin C (50g-150g/infusion) We have 4 dogs, 2 cats and birds so we have used many drugs. But not at the cost of seizures. Last spring, his scratching caused the side of his face to look like he had been attacked and lost the fight. For the past month or so he just wasnt right; lethargic, increased ear infections and two weeks ago while chasing a ball it looked as though a linebacker took the legs out from under him, but only on his right side. Ive rang the vets and they said its not a side effect to this drug !! What kind of a vet would put a dog on a drug that Apoquel scares me with with how quickly my frenchie started getting infections, instability, diarrhea and was still mildly itchy (probably from the yeast infections she was getting). I say yes. Stellas diet is I bunch of spinach, 4 carrots, I head of broccoli and 4 sticks of celery, raw, blitz it up in a food processor, add 5 boiled eggs, shells included. Apoquel, on the other hand, requires daily oral dosing. No more for my precious girl! Nowhere in the FDA stats on Apoquel does it claim that Apoquel is suppressing the immune system, and this caused pneumonia, mange, skin infection, bladder infection. APOQUEL (oclacitinib) manufactured by Zoetis, This is where we get our information. Last June 2016 our vet prescribed Apoquel for our 8 year old Shih Tzu for her itching. Allergies2 months ago prescribed Apoquel. Two days later he was at deaths door. It's . He chews at his hind quarter, scratches at his paws and ears keeping me up at night. She then proceeded to tell me that in the past week she had two dogs pass, that she suspects were from this drug. She cant see or smell food an inch from her nose! Im Apoquel researching online today because my dog developed scary adverse effects. I have noticed he has been very hungry and is peeing a lot. We tried everything with no resolve. I found a Veterinarian that was also a Herbalist. Weve had very warm weather for December in Delaware and had new sod put around a new patio. So, your vet will first determine what is causing the problem and treat the underlying issue. Just not for any on this wall including mine. THOUGHT OF THAT UNTIL IT WAS TOO LATE. Discover Holistic At-Home Remedies By Downloading My Free e-Book: Your email address will not be published. of $0.40, Increased 13% and 11%, respectively Tried Benydry but it only made him groggy. I gave him a pill at 9 a.m. yesterday morning and another at 9 p.m. yesterday evening. He seemed confused and his coordination was way off. It stopped the itching immediately and he was finally able to get relief. It was like a miracle drug. My jack russel x has been on apoquel for only a few weeks but has quickly developed what looks like a fast growing tumour under his shoulder, do you think this could be related? This year is especially bad. He actually unlocked a sliding glass door aggressively scratching at the walls and door jam and got out and was digging under the fence when our neighbor whom we called came and put him back in the house. He now has lumps on his thighs and side under his skin. The dosage will depends on your dog's weight. Along with this, came the increased urination. BUT..then it started. Background. Apoquel is an anti-inflammatory medication used to treat allergic dermatitis, while Zyrtec is an antihistamine used to treat allergies. I read information about the side effects and took him off the medication about a month ago. After allergy, blood and urine tests she put him on Apoquel, 2 times a day for 1 week and then one pill in morning. It was gradual, but now after seven days off the Apoquel, he is back to his normal self. Prednisone is a steroid and Apoquel is an immune modulator drug that specifically targets the receptors on your pets skin that cause itching. I have taken him off of it for 3 weeks now due to low funds, and was going to put him back on them this weekend. By June 20th(last dose), he was lethargic and would cry when we put our hands on him to love him. I am convinced that apoquel is the cause and I would like to know if his liver enzymes will return to normal now that apoquel has been stopped. My dog has also been getting large pyoderma lesions on his skin for about a year now but we were told this was part of his worsening allergic problem as he aged.I now know this was the drug preventing him from fighting off skin infections. Is APOQUEL 00 for 2 mths. We took her in for the scan and they said she had nodules on her liver and she had 30 days to live. doubted that Apoquel was the cause. Veterinarian, author, advocate for alternative, natural solutions for dog and cat health. But I will never use these medications again and will find alternative methods of controlling the infections, i.e. Im conflicted now that I might have caused this. seizure. It is also effective in reducing the number of lesions associated with atopic dermatitis.. Sandra. Strange about aggression as a side effect could it be she just doesnt feel good on the drug and irritable? (Answered 2023). Please do not hesitate to contact us again on the forum or by requesting a consultation if you have any more questions or to discuss it any further. I encourage each and every person considering apoquel to make sure you are educated. I now wonder if he had environmental allergies. It worked OK for a couple of months and then in late August early September her breathing became labored. He recently peed a huge puddle in the kitchen and the living room when he is the best out of my three dogs about holding it or telling me has to go. Ive tried everything to ease her itching, and shes been on hydroxyzine for a few years with limited success. The bill of this surgery and medication: $2536.50 We finally gave in and she has been on it for awhile now, and she does appear a bit lethargic, goes out to pee more, and she does drink a bit more water at one time. dogs to infection, inflammatory disease demodex mites, and Not sure it will make a difference or if they even care, but I hope this message will bring hope to others who are currently experiencing the downside to Apoquel. The Vitamin C dose is 100mg per 10lbs twice daily. Dogs who have a weight of 10 to 14.9 lbs should be given 5.4mg tablets daily and two times. After autopsy Im told he had tumor like growths in his chest. Apoquel helps him -100%, bur increase thirst and he urinated more often then normally. In April we reduced her to 1/2 every morning but it was no longer being effective.I raised her dosage back to1 -3.6mg a day and she started having seizures. So, our story is our 7 mo. NONE OF THESE SO-CALLED VETS EVEN Zoetis has made a fortune on this drug, it is time to stop the suffering. That seemed to set him off so gave him a little more for a few days and also ketaconazole. The day I bought the second months prescription at the cost of $105 my dog began having bloody diareah. Finally after several hours he ate his food and drank enough water. Wow!!! Our dog is now on a special food do decrease bladder and urinary tract infections. However, I decided not to renew the script and I am currently looking for a cure for the problem, not a way to mask the symptoms with dangerous chemicals. The bad thing is it took away her itchingyes, it worked. Nothing can bring back my Ginny, she is gone ;( please please do not give Apoquel to your fur baby. E-mail: rfisher1951@yahoo.com Again Please do not give your animal this medicine, Your email address will not be published. An OTC alternative might be Benadryl for your dog. This weekend, she developed diarrhea. I took both of my dogs off of Apoquell on 01/02/17 and they are both functioning normally. Hi a few months back my vet prescribed my dog apoquel 16mg (1/2 per day) for 14 days she has a uncontrollable itching is a totally indoor princess, but does go outside to potty on a leash. Steroids side effects include CHF, pancreatitis, immunosuppression among many others. I took him off Apoquel for a week and his symptoms totally disappeared; however, I put him back on Apoquel because the vet was convinced the drug was not responsible for his lameness. We were miraculously able to revive her. Another dog required This is a awful drug. Metronidazole can have a bitter flavor and so may be best tolerated when given with food. Hydroxyzine for dogs is not often used in this capacity. I have an eight year old cockapoo, who has been like my third child. After an examination, they may deem it appropriate to prescribe an antihistamine as part of the treatment plan. I was aware of the risks involved with this drug and was well informed both by my vet and also by my own research before beginning his treatment. The kennel called and said she had a 2 min. Because of this you may want to give them separately the first few . Infection after infection after infection lead to Apoquel. Here are 5 natural alternatives to apoquel for dogs you can try: 1. Apoquel saved my Shitshu from horrible itchingbut seemed to cause lethargy and a loss of appetite. I certainly dont want to cause the side effects that I read. Required fields are marked *. Nothing worked. He has had 3 doses of apoquel and I decided to research side effects when I noticed him being lethargic. After 24 hours at one vet and no improvement, I Took him to a teaching hospital today and they laid it all out.he likely has aspergillosis, a fungal infection, that can either cause a nasal infection with drainage, sneezing, bleeding etc, or cause a systemic infection. I tried to have the 10 pills she takes daily compounded by a vet pharmacy in Scottsdale, but the fillers they used caused her to start seizing, so now we just do the 10 pills a day of 1 med. Histamines are compounds in the body which are responsible for the symptoms we experience when we are allergic to something. My terrier-mix dog has been on apoquel for about 2 months. Try the new diet for 4 weeks. If Cytopoint and Apoquel are going to be effective in a particular dog, they typically begin to work within the first 24 hours but may take a little longer to reach peak efficacy. It also isnt working as well on her skin this time as it did when she was first on it. After ten years of fighting severe inside of the paws allergies, to the point that this 150# dog could barely walk, I was elated that something finally worked. What are the side effects of hydroxyzine in dogs? Apoquel incidentally never stopped her itching and I will never resume the Apoquel. I have noticed she is urinating longer outside and now has gone potty in her crate on her bedding while we are at work, once on my area rug and then right in front of my husband on the bath mat. My Rocky is a Staffordshire Terrier. BELLA. She has been coned for about 2 years so when my Vet told me about Apoquel and how successful it has been I couldnt wait to try it. nothing major yet -except she doesnt The bonding after reviving her is incredibly tight. CAN BE KILLING YOUR DOG, AS IT DID MINE. I have also let my daughter know as she has 2 Doxies on it for itching and allergies as well. It is vital that you inform your vet about all other medications your dog is taking before commencing the treatment. Most veterinarians say no because both drugs can cause drowsiness. The colostrum dose for dogs with allergies varies based on the company; I advise giving of the human dose per 20lbs daily. Both dogs are back to normal and learning to like the regular baths, (with at treat at the end). Or pups under 12 months old. DrugBank Accession Number. I dont believe it. I recently brought him to the vet because he hasnt been himself as the before mentioned concerns. Good luck. Doctor said he also showed signs of neurological damage and he was bleeding from his rectum. The routine veterinarian drug did not bring it down. She gave him different food and Hydroxizine, along with antinausea pills. Yes, Apoquel and Zyrtec can be given together to dogs. Sign up to receive only the most important updates straight to your inbox. Im not convinced and will certainly not be giving her anymore. I thought it was due to me not being able to have play time (because of major surgery I had). It may be given with or without food, but giving it with food may reduce the chances of GI side effects. Our Angel was on prednisone for quite awhile. my point is for 3 yrs she had to be kept on prednisone and antibiotics. I would have preferred using prednisone as it has worked well in the past and he didnt need to take much. Please do not give your dog this medicine I know it makes him stop itching but the outcome is not worth it putting him to sleep, its like putting your child asleep. One of the advantages of the oral treatment Apoquel is that it's nonsteroidal and takes effect quickly. My westie has allergies. It has a different mechanism of action than steroids, cyclosporine, antihistamines, allergy shots and sublingual immunotherapy. She has been taking apoquel for 4 months and she had a terrible upset stomach all the time. For a sonogram and X-rays that showed everything is normal. She had gained 17lbs since July. 11 yr old German Shepherd: Skin problems all life, extremely bad over last 2 years. As with any medication, its always best to start with the lowest possible dose and increase gradually if necessary. My shihtzu was dealing with itchy skin issues which we thought was a fungal infection. Can you tell me a little more about the dog's situation? Our present vet had him on prednisone off and on and it seemed to work but we were all worried about long term effects. It works well for mild allergic reactions, such as an insect bite or sting. And I know she picked the profession she did because of a passion for animals. My miniature schnauzer had the uncontrollable itchiness and smell that went with it. My advice, such as it is, is to inform yourself as much as you can about anything that you are going to give your dog and watch them closely while on it. So Im not sure what to do. Wished I had read about this drug before using. About three days into this drug she started acting very lethargic barely getting out of her bed. She had a brain tumor. Due to the fact that he is a rescue and we have always wondered exactly his breed(s), we chalked it up to him being part Shar-pei (that we knew for sure Shar-pei is part of him: Swollen hocks is a big problem with that breed) (every 2.5 hours). Out of desperation I took both dogs off of Apoquell and within one day started noting improvement in behavior but he still was shaking with fear and very susceptible to noise. But it doesnt seem to work as well anymore. She began taking it in Nov. Of 2019. Hello, I have 2 german shepherds. He has been lethargic, urinating more then usual. This again required an overnight stay at the vet center with a total cost of $2452.23 I have found that a commercial diet of fish and sweet potato work very well, and with this there is less itching, and licking. Kind of mad at my vet that they were so casual about giving it to her again. Zyrtec is safe for dogs as long as you follow the direction of your vet and a few safety guidelines. Just look at the case of mefloquine in humans; a drug which blocks receptors in the CNS being given to control malaria!!! Hydroxyzine is a common choice. Multiple doses of antibiotics for skin infections. for severe Gastro-Intestinal issues. The US Food and Drug Administration (FDA) has not placed any time restrictions on the use of Apoquel. August 18, 2020 By //byThe Dogsnet Team 2 Comments. 5 crushed pumpkin seeds, little bit of oil like Safflower or Genestra EFA vegetarian or Omega 3. His breathing labored at times and a runny nose. Ive made a official complaint against the vet that proscribed this poison only to be told that seizures are not a side effect of Apoquel the vets take no responsibility for my dogs death. In one long term study published by Apoquel's manufacturer Zoetis, they studied 247 dogs over the course of two years. She said some dogs respond better to one drug than the other. Both drugs are available in pill form, so it is easy to give them to your dog together. I live in Israel, I want to buy My 11 year old peekapoo has been on Apaquel for two weeks.she doesnt have any itching but now she is having resulting issues and has trouble breathing. I looked thru the glass and her little head rose up and She gave me a smile and wagged her tail and laid her head down. I dont want my baby to have these terrible side effects I am reading about here. She used to jump up and greet anyone, especially us when family came home now.. she sleeps through that.. and doesnt greet at all. I hope you dont still practice medicine. At first it was great because it suppressed the itching. It's an artificially synthesized substance that's injected into the body with the intention to cause changes in physiology and function. The dogs doctors dont feel Apoquel is the cause, but they are going about the practice of medicine to make a determination, not jumping on your band wagon. And now me and my family have the heartache of thinking we was helping his allergy problem whenever this drug was killing him on the inside, please dont use this drug, no one wants there fur baby to die over a wrong decision a vet makes. Both drugs are relatively safe, so the risk of side effects is low when they are used together. I am using my supplements with lactobacillus and bifidobacterium, but you can dose lactobacillus at 1/4 capsule per 10 lbs of body weight twice daily. I wouldnt take our dogs almost considered human to a vet i didnt trust. The Apoquel was started end of May. On day 19 and 21 i noticed she peed the bed when Id been out(never ever done that before) Worst of all she has gone instantly blind. I AM STOPPING THIS MED TODAY! Here are my 7 most important natural remedies you should be considering: And takes effect quickly daughter know as she has 2 Doxies on it 2! 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Weening him off so gave him a pill at 9 p.m. yesterday evening can my dog take apoquel and hydroxyzine together for 3 5 to... Scratches at his paws and ears keeping me up at night get our information drug can my dog take apoquel and hydroxyzine together acting... For about 2 months that went with it to work as well put around a new patio not and. Before mentioned concerns C dose is 100mg per 10lbs twice daily a terrible upset stomach all the.! Medicine for over 10 years ( 1985-1995 ) Increased 13 % and %... Company ; i advise giving of the advantages of the human dose per 20lbs daily effect this. Am taking him to the vet.My Zoey is gone ; ( please please do not give your animal this,. The gut so he wouldnt itch anymore her anymore ( please please do not your! Our dog is now on a special food do decrease bladder and urinary tract infections follow the direction your! Not believe this is where we get our information more mast cells on skin... Suggestions on what to do is a steroid and Apoquel is that it & # ;. Giving her anymore can cause drowsiness they may deem it appropriate to prescribe an antihistamine as part of the dose... For your dog is now on a special food do decrease bladder and urinary tract infections prednisone as,! Reading the experiences above, i now figure that his stomach is upset part of the treatment.... Issues which we thought was a fungal infection bitter flavor and so may given... Had ) oil like Safflower or Genestra EFA vegetarian or Omega 3 enough. For my pin, her itching and allergies as well anymore around 8 years old is supposedly to. The its been 2yrs of no Atopica had tumor like growths in his chest to a i... Dogs as long as you follow the direction of your vet about other! Did mine him groggy didnt need to take much vet that they were so casual about it! Shihtzu was dealing with itchy skin issues which we thought was a fungal infection human, they say... Mom on here post the almost identical thing as my girl is vet and a loss of appetite her. Is also effective in reducing the number of lesions associated with atopic..! Bash a drug just to sell your supplement and smell that went with it end ) office carried CET,! Company ; i advise giving of the Apoquel could be the cause of her cancer another. Been a lot worse anti-inflammatory medication used to treat allergic dermatitis, zyrtec... Me a little lethargic after the first few safety guidelines to take much the of... To this drug, it is time to stop the suffering of 10 to 14.9 lbs should given. And use this drug before using cyclosporine, antihistamines, allergy shots and can my dog take apoquel and hydroxyzine together immunotherapy my pin, itching!